ANTIOXIDANT AND GLUCOSIDASE INHIBITION ACTIVITIES AND POLYPHENOL CONTENT OF FIVE SPECIES OF AGRIMONIA GENUS

Abstract

Phytochemical analysis and a comparative study of antioxidant activity, inhibition of a-glucosidase and content of total polyphenols and flavonoids were established in five species of Agrimonia genus. Plants were collected in Medicinal Herbs Centre of Masaryk university Brno and these were Agrimonia eupatoria L., Agrimonia procera Wallr., Agrimonia leucantha Kunze, Agrimonia japonica (Miq.) Koidz and Agrimonia coreana Nakai. HPLC profile of Agrimonia herbs shows high content of quercetin and apigenin glycosides. The content of total polyphenols correlates with antioxidant activity and the content of flavonoids correlates with inhibition of a-glucosidase. Agrimonia procera works as an excellent antioxidant, the most used in traditional medicine Agrimonia eupatoria is richer on flavonoid glycosides.